Genetic Bottlenecks Reduce Disease Resistance in South China Tigers

A single virus could threaten an entire subspecies.

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🤯 Did You Know (click to read)

Genetic diversity in immune system genes directly influences population-level disease resistance.

Severe genetic bottlenecks reduce overall immune system diversity within the South China tiger population. Limited variation in key immune genes can heighten vulnerability to pathogens. In larger, genetically diverse populations, some individuals typically resist emerging diseases. In a bottlenecked population, susceptibility can be widespread. Captive management includes veterinary monitoring to mitigate outbreaks. However, confined settings can also facilitate disease transmission. The combination creates a delicate balance between protection and risk.

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💥 Impact (click to read)

Disease outbreaks have historically devastated wildlife populations, even those numbering in the thousands. For a predator population already below a few hundred, the margin for error is minimal. Vaccination protocols and quarantine measures are essential but not foolproof. A novel pathogen could exploit uniform immune profiles. The threat is magnified because there is no wild reservoir population to buffer losses.

This vulnerability underscores why genetic diversity functions as biological armor. Without it, evolutionary adaptability contracts sharply. Conservation strategies must therefore integrate genomics with veterinary science. The South China tiger’s future hinges not just on habitat restoration but on maintaining immune resilience. In a globally connected world, disease risk remains a constant pressure on small populations.

Source

Proceedings of the National Academy of Sciences

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